兔抗CTNND2多克隆抗体

Background:

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, WB

Name of antibody:

CTNND2

Immunogen:

Synthetic peptide of human CTNND2

Full name:

catenin delta 2

Synonyms:

GT24; NPRAP

SwissProt:

Q9UQB3

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

133 kDa

WB Positive control:

Mouse brain tissue and Human cerebrum tissue lysates

WB Recommended dilution:

200-1000