兔抗CDKN2B多克隆抗体

Background:

This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression.

Applications:

WB, IHC, IF

Name of antibody:

CDKN2B

Immunogen:

Synthesized peptide derived from human p15 INK antibody.

Full name:

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Synonyms：

P15; MTS2; TP15; CDK4I; INK4B; p15INK4b

SwissProt:

P42772

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

15 kDa

WB Positive control:

Hela cells lysate

WB Recommended dilution:

500-3000

IF positive control:

Hela cells

IF Recommend dilution:

100-500