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Background: |
This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DCD |
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Immunogen: |
Fusion protein of human DCD |
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Full name: |
dermcidin |
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Synonyms: |
PIF; AIDD; DSEP; HCAP; DCD-1 |
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SwissProt: |
P81605 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
30-150 |
