兔抗ACP6多克隆抗体

Background:

Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Applications:

ELISA, IHC

Name of antibody:

ACP6

Immunogen:

Fusion protein of human ACP6

Full name:

acid phosphatase 6, lysophosphatidic

Synonyms:

LPAP; ACPL1; PACPL1

SwissProt:

Q9NPH0

IHC positive control:

Human gastric cancer and human prostate cancer

IHC Recommend dilution:

50-200