兔抗LIG1多克隆抗体

Background:

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

LIG1

Immunogen:

Fusion protein of human LIG1

Full name:

ligase I, DNA, ATP-dependent

SwissProt:

P18858

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human esophagus cancer and Human breast cancer

IHC Recommend dilution:

100-300