小鼠抗JPH2单克隆抗体

Background:

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described.

Applications:

WB

Name of antibody:

JPH2

Immunogen:

Fusion protein of human JPH2

Full name:

junctophilin 2 (JPH2), transcript variant 1

Synonyms:

CMH17; JP-2; JP2

SwissProt:

Q9BR39

WB Predicted band size:

74 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK cell lysates

WB Recommended dilution:

500-2000