兔抗HOXD4多克隆抗体

Background:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in determining positional values in developing limb buds. Alternatively spliced variants have been described but their full length nature has not been determined.

Applications:

ELISA, IHC

Name of antibody:

HOXD4

Immunogen:

Synthetic peptide of human HOXD4

Full name:

homeobox D4

Synonyms:

HOX4; HOX4B; HHO.C13; HOX-5.1; Hox-4.2

SwissProt:

P09016

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human breast cancer

IHC Recommend dilution:

10-50