兔抗RNF20多克隆抗体

Background:

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.

Applications:

ELISA, WB, IHC

Name of antibody:

RNF20

Immunogen:

Fusion protein of human RNF20

Full name:

ring finger protein 20, E3 ubiquitin protein ligase

Synonyms：

BRE1; BRE1A; hBRE1

SwissProt:

Q5VTR2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human colon cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

114 kDa

WB Positive control:

Hela, Jurkat, 231, A375, A172 and Lovo cells

WB Recommended dilution:

500-2000