兔抗CNST多克隆抗体

Background:

Targeting of numerous transmembrane proteins to the cell surface is thought to depend on their recognition by cargo receptors that interact with the adaptor machinery for anterograde traffic at the distal end of the Golgi complex. Consortin (CNST) is an integral membrane protein that acts as a binding partner of connexins, the building blocks of gap junctions, and acts as a trans-Golgi network (TGN) receptor involved in connexin targeting to the plasma membrane and recycling from the cell surface (del Castillo et al., 2010 [PubMed 19864490]).

Applications:

ELISA, IHC

Name of antibody:

CNST

Immunogen:

Fusion protein of human CNST

Full name:

consortin, connexin sorting protein

Synonyms:

C1orf71; PPP1R64

SwissProt:

Q6PJW8

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and Human brain

IHC Recommend dilution:

50-200