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标 记 物： Unconjugate
技术规格
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Background: |
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
HLA-E |
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Immunogen: |
Fusion protein of human HLA-E |
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Full name: |
major histocompatibility complex, class I, E |
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Synonyms: |
QA1; HLA-6.2 |
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SwissProt: |
P13747 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and Human colorectal cancer |
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IHC Recommend dilution: |
50-300 |
