兔抗ITGB1(Phospho-Thr789) 多克隆抗体

Background:

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

Applications:

WB, IHC

Name of antibody:

ITGB1(Phospho-Thr789)

Immunogen:

Peptide sequence around phosphorylation site of threonine 789(V-E-T(p)-V-V) derived from Human Integrin β1 .

Full name:

integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

Synonyms：

CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA

SwissProt:

P05556

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

88 kDa

WB Positive control:

HepG2 cells lysates treated with Ca2+

WB Recommended dilution:

500-1000