| Background: | The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. | 
| Applications: | ELISA, WB, IHC | 
| Name of antibody: | SUFU | 
| Immunogen: | Fusion protein of human SUFU | 
| Full name: | SUFU negative regulator of hedgehog signaling | 
| Synonyms: | SUFUH; JBTS32; SUFUXL; PRO1280 | 
| SwissProt: | Q9UMX1 | 
| ELISA Recommended dilution: | 1000-2000 | 
| IHC positive control: | Human thyroid cancer and Human colon cancer | 
| IHC Recommend dilution: | 15-50 | 
| WB Predicted band size: | 54 kDa | 
| WB Positive control: | Jurkat cells | 
| WB Recommended dilution: | 200-1000 | 
	
	
 
 
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 021-54845833/15800441009
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