兔抗HIST1H2AE多克隆抗体

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Applications:

ELISA, WB, IHC

Name of antibody:

HIST1H2AE

Immunogen:

KLH conjugated synthetic peptide derived from human Histone H2A

Full name:

histone cluster 1, H2ae

Synonyms：

H2A.1; H2A.2; H2A/a; H2AFA

SwissProt:

P04908

ELISA Recommended dilution:

500-1000

WB Recommended dilution:

100-500