小鼠抗NEK9单克隆抗体

Background:

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.

Applications:

WB, IF, FC

Name of antibody:

NEK9

Immunogen:

Fusion protein of human NEK9

Full name:

NIMA-related kinase 9 (NEK9)

Synonyms:

Nek8; NERCC; NERCC1

SwissProt:

Q8TD19

WB Predicted band size:

107 kDa

WB Positive control:

HepG2, Hela, A549, COS7, Jurkat, MDCK cell lysates

WB Recommended dilution:

500-2000