小鼠抗MICU1单克隆抗体

Background:

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications:

WB, IHC

Name of antibody:

MICU1

Immunogen:

Fusion protein of human MICU1

Full name:

mitochondrial calcium uptake 1

Synonyms:

CALC; EFHA3; MPXPS; CBARA1; ara CALC

SwissProt:

Q9BPX6

IHC positive control:

Human liver cancer and Human thyroid cancer; Human colorectal cancer and Human gastric cancer

IHC Recommend dilution:

100-500

WB Predicted band size:

54 kDa

WB Positive control:

A549, Hela, K562 and 231 cell lysates

WB Recommended dilution:

1000-5000