兔抗AK1多克隆抗体

Background:

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

Applications:

ELISA, WB, IHC

Name of antibody:

AK1

Immunogen:

Fusion protein of human AK1

Full name:

adenylate kinase 1

Synonyms：

HTL-S-58j

SwissProt:

P00568

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and human breast cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

22 kDa

WB Positive control:

HT-29 cells

WB Recommended dilution:

500-1000