兔抗HIRIP3多克隆抗体

Background:

The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

HIRIP3

Immunogen:

Fusion protein of human HIRIP3

Full name:

HIRA interacting protein 3

SwissProt:

Q9BW71

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human tonsil

IHC Recommend dilution:

50-300