小鼠抗MAPK13单克隆抗体

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

MAPK13

Immunogen:

Fusion protein of human MAPK13

Full name:

mitogen-activated protein kinase 13 (MAPK13), transcript variant 1

Synonyms:

MAPK 13; MAPK-13; p38delta; PRKM13; SAPK4

SwissProt:

O15264

IHC positive control:

human pancreas tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

42 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

200-1000