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021-54845833/15800441009
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Background: |
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DOK7 |
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Immunogen: |
Synthetic peptide of human DOK7 |
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Full name: |
docking protein 7 |
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Synonyms： |
CMS10; CMS1B; C4orf25 |
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SwissProt: |
Q18PE1 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
