兔抗LILRB5多克隆抗体

Background:

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

LILRB5

Immunogen:

Synthetic peptide of human LILRB5

Full name:

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5

Synonyms:

LIR8; CD85C; LIR-8

SwissProt:

O75023

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

64 kDa

WB Positive control:

HepG2 cell lysate

WB Recommended dilution:

500-2000