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Background: |
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
LILRB5 |
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Immunogen: |
Synthetic peptide of human LILRB5 |
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Full name: |
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 |
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Synonyms: |
LIR8; CD85C; LIR-8 |
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SwissProt: |
O75023 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
10-50 |
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WB Predicted band size: |
64 kDa |
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WB Positive control: |
HepG2 cell lysate |
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WB Recommended dilution: |
500-2000 |
