小鼠抗JUP单克隆抗体

Background:

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

Applications:

WB, IHC

Name of antibody:

JUP

Immunogen:

Fusion protein of human JUP

Full name:

junction plakoglobin

Synonyms:

DP3; PDGB; PKGB; CTNNG; DPIII

SwissProt:

P14923

IHC positive control:

Human kidney tissue and Human liver tissue

IHC Recommend dilution:

500-2000

WB Predicted band size:

82 KD

WB Positive control:

Hela and A431 cell lysates

WB Recommended dilution:

200-1000