兔抗HTR2B多克隆抗体

Background:

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

Applications:

ELISA, IHC

Name of antibody:

HTR2B

Immunogen:

Fusion protein of human HTR2B

Full name:

5-hydroxytryptamine receptor 2B

Synonyms:

5-HT2B, 5-HT(2B)

SwissProt:

P41595

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

100-300