小鼠抗DNM1L单克隆抗体

Background:

The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC, IF

Name of antibody:

DNM1L

Immunogen:

Fusion protein of human DNM1L

Full name:

dynamin 1-like (DNM1L), transcript variant 1

Synonyms:

DLP1; DRP1; DVLP; DYMPLE; EMPF; HDYNIV

SwissProt:

O00429

IHC positive control:

human pancreas tissue and adenocarcinoma of human breast tissue; human bladder tissue and human kidney tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

82 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000