小鼠抗DOK7单克隆抗体

Background:

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

Applications:

WB, IF, FC

Name of antibody:

DOK7

Immunogen:

Fusion protein of human DOK7

Full name:

docking protein 7 (DOK7), transcript variant 1

Synonyms:

CMS10; CMS1B; C4orf25

SwissProt:

Q18PE1

WB Predicted band size:

53 kDa

WB Positive control:

SVT2 cell lysate

WB Recommended dilution:

200-1000