兔抗BAK1多克隆抗体

Background:

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

Applications:

ELISA, WB, IHC

Name of antibody:

BAK1

Immunogen:

Fusion protein of human BAK1

Full name:

BCL2-antagonist/killer 1

Synonyms：

BAK; CDN1; BCL2L7; BAK-LIKE

SwissProt:

Q16611

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human breast cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

23 kDa

WB Positive control:

Hela, A431, 293T and Jurkat cells

WB Recommended dilution:

1000-5000