兔抗EIF4A3多克隆抗体

Background:

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Applications:

ELISA, WB, IHC

Name of antibody:

EIF4A3

Immunogen:

Fusion protein of human EIF4A3

Full name:

eukaryotic translation initiation factor 4A3

Synonyms:

RCPS; DDX48; MUK34; NUK34; NMP265; eIF4AIII

SwissProt:

P38919

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human breast cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

47 kDa

WB Positive control:

Raji, Hela, A549, HEPG2 and 231 cell lysates

WB Recommended dilution:

500-2000