小鼠抗SOD2单克隆抗体

Background:

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

Applications:

WB

Name of antibody:

SOD2

Immunogen:

Fusion protein of human SOD2

Full name:

superoxide dismutase 2

Synonyms:

IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD

SwissProt:

P04179

WB Predicted band size:

25 kDa

WB Positive control:

Hela, THP-1, A549, Ramos and K562 cell lysates

WB Recommended dilution:

1000-5000