小鼠抗HBB单克隆抗体

Background:

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Applications:

ELISA, WB, IHC

Name of antibody:

HBB

Immunogen:

human hemoglobin

Full name:

hemoglobin, beta

Synonyms：

CD113t-C; beta-globin

SwissProt:

P68871

ELISA Recommended dilution:

500-1000

WB Recommended dilution:

100-500