兔抗BIRC5多克隆抗体

Background:

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

BIRC5

Immunogen:

Fusion protein of human BIRC5

Full name:

baculoviral IAP repeat containing 5

Synonyms:

API4; EPR-1

SwissProt:

O15392

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human prostate cancer and Human esophagus cancer

IHC Recommend dilution:

100-300