兔抗ACTC1多克隆抗体

Background:

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Applications:

ELISA, IHC

Name of antibody:

ACTC1

Immunogen:

Fusion protein of human ACTC1

Full name:

actin, alpha, cardiac muscle 1

Synonyms:

ACTC; ASD5; CMD1R; CMH11; LVNC4

SwissProt:

P68032

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human tonsil

IHC Recommend dilution:

50-200