兔抗LRP5多克隆抗体

Background:

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Applications:

ELISA, IHC

Name of antibody:

LRP5

Immunogen:

Synthetic peptide of human LRP5

Full name:

low density lipoprotein receptor-related protein 5

Synonyms：

HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, OPTA1, VBCH2

SwissProt:

O75197

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human ovarian cancer

IHC Recommend dilution:

100-300