小鼠抗ACSL5单克隆抗体

Background:

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

ACSL5

Immunogen:

Fusion protein of human ACSL5

Full name:

acyl-CoA synthetase long chain family member 5

Synonyms:

ACS2; ACS5; FACL5

SwissProt:

Q9ULC5

WB Predicted band size:

76 KD

WB Positive control:

Mouse brain tissue lysate

WB Recommended dilution:

500-2000