兔抗PRKCD(Ab-64)多克隆抗体

Background:

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Applications:

WB

Name of antibody:

PRKCD(Ab-64)

Immunogen:

Synthesized non-phosphopeptide derived from human PKCD around the phosphorylation site of tyrosine 64 (H-I-Y(p)-E-G).

Full name:

protein kinase C, delta

Synonyms：

MAY1; PKCD; CVID9; nPKC-delta

SwissProt:

Q05655

WB Predicted band size:

78 kDa

WB Positive control:

NIH/3T3 cells treated with EGF (200ng/ml, 30mins) lysate

WB Recommended dilution:

500-3000