兔抗NSD2多克隆抗体

Background:

This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]

Applications:

ELISA, IHC

Name of antibody:

NSD2

Immunogen:

Synthetic peptide of human NSD2

Full name:

nuclear receptor binding SET domain protein 2

Synonyms:

WHS; TRX5; KMT3F; KMT3G; MMSET; WHSC1; REIIBP

SwissProt:

O96028

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

25-100