兔抗RGS1多克隆抗体

Background:

This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Applications:

ELISA, WB, IHC

Name of antibody:

RGS1

Immunogen:

Fusion protein of human RGS1

Full name:

regulator of G-protein signaling 1

Synonyms：

1R20; BL34; IER1; IR20; HEL-S-87

SwissProt:

Q08116

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human prostate cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

24 kDa

WB Positive control:

RAW264.7 cells

WB Recommended dilution:

500-2000