兔抗CD46多克隆抗体

Background:

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.

Applications:

ELISA, IHC

Name of antibody:

CD46

Immunogen:

Fusion protein of human CD46

Full name:

CD46 molecule, complement regulatory protein

Synonyms：

MCP; TLX; AHUS2; MIC10; TRA2.10

SwissProt:

P15529

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

25-100