小鼠抗LMNB2单克隆抗体

Background:

This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Applications:

WB, IP

Name of antibody:

LMNB2

Immunogen:

Fusion protein of human LMNB2

Full name:

lamin B2

Synonyms:

EPM9; LMN2; LAMB2

SwissProt:

Q03252

WB Predicted band size:

70 kDa

WB Positive control:

HCT116, Mouse Embryo and Jurkat cell lysates

WB Recommended dilution:

500-2000