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Background: |
The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region. [provided by RefSeq]. COMPLETENESS: complete on the 3' end. |
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Applications: |
WB, IHC |
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Name of antibody: |
PPAT |
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Immunogen: |
Fusion protein of human PPAT |
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Full name: |
phosphoribosyl pyrophosphate amidotransferase (PPAT) |
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Synonyms: |
ATASE; GPAT; PRAT |
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SwissProt: |
Q06203 |
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IHC positive control: |
human liver tissue and carcinoma of human liver tissue; human pancreas tissue and carcinoma of human thyroid tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
57 kDa |
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WB Positive control: |
Human testis tissue, Human omentum tissue, Human uterus tissue, Human brain tissue, Human ovary tissue lysates |
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WB Recommended dilution: |
200-1000 |
