兔抗CAV2(Phospho-Tyr27)多克隆抗体

Background:

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]

Applications:

WB

Name of antibody:

CAV2(Phospho-Tyr27)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 27 (L-E-Y(p)-A-D) derived from Human Caveolin 2.

Full name:

caveolin 2

Synonyms：

CAV

SwissProt:

P51636

WB Predicted band size:

18 kDa

WB Positive control:

COS7 cells lysates

WB Recommended dilution:

500-1000