兔抗DDX19B多克隆抗体

Background:

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

DDX19B

Immunogen:

Fusion protein of human DDX19B

Full name:

DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B

Synonyms：

DBP5; RNAh; DDX19

SwissProt:

Q9UMR2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil and human breast cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

54 kDa

WB Positive control:

Hela and 293T cells

WB Recommended dilution:

500-2000