兔抗BCL2L12多克隆抗体

Background:

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants

Applications:

ELISA, IHC

Name of antibody:

BCL2L12

Immunogen:

Fusion protein of human BCL2L12

Full name:

BCL2-like 12 (proline rich)

SwissProt:

Q9HB09

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human thyroid cancer and human gastric cancer

IHC Recommend dilution:

25-100