兔抗ILK(Ab-246) 多克隆抗体

Background:

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants

Applications:

WB, IHC

Name of antibody:

ILK(Ab-246)

Immunogen:

Synthesized non-phosphopeptide derived from human ILK around the phosphorylation site of serine 246 (I-F-S(p)-H-P).

Full name:

integrin-linked kinase

Synonyms：

P59; ILK-1; ILK-2; p59ILK; HEL-S-28

SwissProt:

Q13418

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

51 kDa

WB Positive control:

Rat liver tissue lysate

WB Recommended dilution:

500-3000