兔抗IRS1(Phospho-Ser307) 多克隆抗体

Background:

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit

Applications:

IHC

Name of antibody:

IRS1(Phospho-Ser307)

Immunogen:

Peptide sequence around phosphorylation site of serine 307(T-E-S(p)-I-T) derived from Human IRS-1.

Full name:

insulin receptor substrate 1

Synonyms：

HIRS-1

SwissProt:

P35568

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100