兔抗ATXN7L3多克隆抗体

Background:

Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

Applications:

ELISA, WB, IHC

Name of antibody:

ATXN7L3

Immunogen:

Fusion protein of human ATXN7L3

Full name:

ataxin 7-like 3

SwissProt:

Q14CW9

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain and human esophagus cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

39 kDa

WB Positive control:

Hela and Raji cell lysates

WB Recommended dilution:

500-2000