兔抗ASIC3多克隆抗体

Background:

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.

Applications:

ELISA, IHC

Name of antibody:

ASIC3

Immunogen:

Synthetic peptide of human ASIC3

Full name:

acid sensing (proton gated) ion channel 3

Synonyms：

ACCN3; TNaC1; DRASIC; SLNAC1

SwissProt:

Q9UHC3

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

30-150