小鼠抗TBCC单克隆抗体

Background:

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq].

Applications:

WB, IHC, IF

Name of antibody:

TBCC

Immunogen:

Fusion protein of human TBCC

Full name:

tubulin folding cofactor C (TBCC)

Synonyms:

CFC

SwissProt:

Q15814

IHC positive control:

adenocarcinoma of human ovary tissue and human pancreas tissue; adenocarcinoma of human endometrium tissue and adenocarcinoma of human colon tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

39 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000