| Background: | This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. | 
| Applications: | ELISA, IHC | 
| Name of antibody: | TMEM123 | 
| Immunogen: | Fusion protein of human TMEM123 | 
| Full name: | transmembrane protein 123 | 
| Synonyms: | KCT3; PORMIN; PORIMIN | 
| SwissProt: | Q8N131 | 
| ELISA Recommended dilution: | 2000-10000 | 
| IHC positive control: | Human liver cancer | 
| IHC Recommend dilution: | 30-150 | 
	
	 
 
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