小鼠抗PDE1B单克隆抗体

Background:

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM].

Applications:

WB, IHC, IF, FC

Name of antibody:

PDE1B

Immunogen:

Fusion protein of human PDE1B

Full name:

phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1

Synonyms:

PDE1B1; PDES1B; HEL-S-79p

SwissProt:

Q01064

IHC positive control:

human kidney tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

61 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

500-2000