兔抗PPP1R1A多克隆抗体

Background:

Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Applications:

ELISA, IHC

Name of antibody:

PPP1R1A

Immunogen:

Fusion protein of human PPP1R1A

Full name:

protein phosphatase 1 regulatory inhibitor subunit 1A

Synonyms:

I1; IPP1

SwissProt:

Q13522

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human brain

IHC Recommend dilution:

50-300