兔抗TCEB3多克隆抗体

Background:

his gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Applications:

WB, IHC

Name of antibody:

TCEB3

Immunogen:

Synthesized peptide derived from internal of human ELOA1.

Full name:

transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)

Synonyms：

EloA; SIII; TCEB3A; SIII p110

SwissProt:

Q14241

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

90 kDa

WB Positive control:

Jurkat cells and Huvec cells lysates

WB Recommended dilution:

500-3000